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Normally lectures will be made available at the beginning of the week. Week numbers are sequential per term. Each TERM roughly coincides with a particular unit. There will be deviations for a few individual lectures, in order to pace delivery of more difficult subjects. Some "weeks" in Terms 1 and 2 have a release which is intended to be studied over a 2-week period. "Weeks" and "Lectures" in Term 3 are only nominal, as the projects are self-paced.

Official start date November 7th.
Please complete enrolment including payment by Thursday December 1st. Closure date for applications Thursday December 1st.

TERM 1 (Unit 1: Fundamentals of Protein Structure and X-ray Crystallography)
Week	Date	Lecture	Topic	Lecturer responsible
1-2	07-11	Introduction & Web Authoring	Overview of Protein Crystallography & Bioinformatics (RasMol, Mime, HTML, Images, BioMOO)	TEB
1-2	07-11	Protein Structure I	Primary Structure & Amino Acid and Peptide Bond Geometry	TEB
1-2	07-11	Protein Structure II	Non-Covalent (Non-Bonded) Interactions	TEB
3	21-11	Protein Structure III	Secondary Structure, Super Secondary Structure and Tertiary Structure	AB
4	28-11	Protein Structure IV	Quaternary Structure (Point Groups)	AB, JKC
5	5-12	X-Ray Diffraction I and the CCP4 Gui	Diffraction Theory (Scattering, Unit Cell, Braggs Law, Reciprocal Space, Indices, Structure Factor) and using the CCP4 Gui	TEB
Christmas Break
6	9-1	Symmetry I	Symmetry Operations (Rotational, Translational, Screw, Symbols, Unit Cell)	JKC, TEB
7-8	16-1	Symmetry II	Point Groups (Enantiomorphic, Polar, Laue Classes)	JKC, TEB
9	30-1	Protein Crystallography I	Protein Crystallisation	AB
10-11	6-2	Symmetry III	Space Groups (Enantiomorphic, Asymmetric Unit, P21, P212121)	JKC, TEB
12	20-2	Protein Crystallography II	X-Rays, X-Ray Sources (Laboratory, Synchrotron) & X-Ray Detectors (Image Plate, CCD).	AB, JKC
Break
TERM 2 (Unit 2: Protein Crystallography)
Week	Date	Lecture	Topic	Lecturer responsible
13	13-3	Protein Crystallography III	Data Collection (Oscillation Method) & Cryocrystallography	AB
2-3	20-3	Symmetry IV & Protein Crystallography IV	Extinctions, Space Group Determination & Data Processing	TEB, JKC
Easter Break
4-5	17-4	X-Ray Diffraction II	Fourier Transforms (Synthesis, Analysis, Convolutions, Correlations)	TEB
6	2-5	Protein Crystallography V & X-Ray Diffraction III	Molecular Replacement (Rotation Function, Translation Function), Patterson	TEB
7	8-5	Protein Crystallography VI	Isomorphous Replacement, Patterson	AB
8-9	15-5	Protein Crystallography VII & X-Ray Diffraction V	MAD, Anomalous Diffraction	AB
10	30-5	Protein Crystallography VIII	Density Modification	NQM
11	5-6	Protein Crystallography IX	Electron Density Map, Modelling & Refinement	NQM
12	12-6	Protein Crystallography X	Validation & PDB	AB
TERM 3 (Unit 3: Project)
Week	Date	Lecture	Topic	Lecturer responsible
1	19-6	Protein Crystallography XI & Project A	Papers & Understanding Crystallographic Results Project A Paper Abstract	TEB
1	26-6	Project B	Project B Molecular Replacement	TEB
1-10	Months 6/7/8/9/10	Project A & B	Project Work	TEB
Break
September 21st	WRITTEN EXAMINATIONS
Break
October	SUBMISSION OF PROJECT WORK
by Christmas	CERTIFICATES AWARDED

Course Index