Protein Crystallography Clickable Map

Advanced  Certificate  in  Protein  Crystallography  on  the  Web 
Timetable  Lectures  05/06 

School of CrystallographyBirkbeck College
University of London

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Normally lectures will be made available at the beginning of the week. Week numbers are sequential per term. Each TERM roughly coincides with a particular unit. There will be deviations for a few individual lectures, in order to pace delivery of more difficult subjects. Some "weeks" in Terms 1 and 2 have a release which is intended to be studied over a 2-week period. "Weeks" and "Lectures" in Term 3 are only nominal, as the projects are self-paced.

Official start date November 7th.
Please complete enrolment including payment by Thursday December 1st. Closure date for applications Thursday December 1st.

TERM 1 (Unit 1: Fundamentals of Protein Structure and X-ray Crystallography)
WeekDateLecture TopicLecturer responsible
1-2 07-11 Introduction & Web Authoring Overview of Protein Crystallography & Bioinformatics (RasMol, Mime, HTML, Images, BioMOO) TEB
1-2 07-11 Protein Structure I Primary Structure & Amino Acid and Peptide Bond Geometry TEB
1-2 07-11 Protein Structure II Non-Covalent (Non-Bonded) Interactions TEB
3 21-11 Protein Structure III Secondary Structure, Super Secondary Structure and Tertiary Structure AB
4 28-11 Protein Structure IV Quaternary Structure (Point Groups) AB, JKC
5 5-12 X-Ray Diffraction I and the CCP4 Gui Diffraction Theory (Scattering, Unit Cell, Braggs Law, Reciprocal Space, Indices, Structure Factor) and using the CCP4 Gui TEB
Christmas Break
6 9-1 Symmetry I Symmetry Operations (Rotational, Translational, Screw, Symbols, Unit Cell) JKC, TEB
7-8 16-1 Symmetry II Point Groups (Enantiomorphic, Polar, Laue Classes) JKC, TEB
9 30-1 Protein Crystallography I Protein Crystallisation AB
10-11 6-2 Symmetry III Space Groups (Enantiomorphic, Asymmetric Unit, P21, P212121) JKC, TEB
12 20-2 Protein Crystallography IIX-Rays, X-Ray Sources (Laboratory, Synchrotron) & X-Ray Detectors (Image Plate, CCD). AB, JKC
TERM 2 (Unit 2: Protein Crystallography)
WeekDateLecture TopicLecturer responsible
13 13-3 Protein Crystallography III Data Collection (Oscillation Method) & Cryocrystallography AB
2-3 20-3 Symmetry IV & Protein Crystallography IV Extinctions, Space Group Determination & Data Processing TEB, JKC
Easter Break
4-5 17-4 X-Ray Diffraction II Fourier Transforms (Synthesis, Analysis, Convolutions, Correlations) TEB
6 2-5 Protein Crystallography V & X-Ray Diffraction III Molecular Replacement (Rotation Function, Translation Function), Patterson TEB
7 8-5 Protein Crystallography VI Isomorphous Replacement, Patterson AB
8-9 15-5 Protein Crystallography VII & X-Ray Diffraction V MAD, Anomalous Diffraction AB
10 30-5 Protein Crystallography VIII Density Modification NQM
11 5-6 Protein Crystallography IX Electron Density Map, Modelling & Refinement NQM
12 12-6 Protein Crystallography X Validation & PDB AB
TERM 3 (Unit 3: Project)
WeekDate Lecture TopicLecturer responsible
1 19-6 Protein Crystallography XI & Project A Papers & Understanding Crystallographic Results
Project A Paper Abstract
1 26-6 Project B Project B Molecular Replacement TEB
1-10 Months 6/7/8/9/10 Project A & B Project Work TEB

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