Why does not every protein sample produce a protein structure? We will show you the bottlenecks and pitfalls.

Steps Overview Protein Structure Diffraction Theory Symmetry Computer Programs Purification Crystallisation X-Ray Sources and Area Detectors Data Collection and Cryocrystallography Data Processing and Space Group Determination Molecular Replacement Isomorphous Replacement MAD Phasing Density Modification Modelling Refinement Validation Databases Paper Contents Protein Structure

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