Department of Crystallography,
Birkbeck College,
University of London
Timetable BioMOOs & Assignments
Normally lectures will be made available at the beginning of the week. Week numbers are sequential per term. Each TERM roughly coincides with a particular unit. There will be deviations for a few individual lectures, in order to pace delivery of more difficult subjects. Certain "weeks" in Terms 1 and 2 have a release which is intended to be studied over a 2-week period. "Weeks" and "Lectures" in Term 3 are only nominal, as the projects are self-paced.
Official start date was Monday November 16th.
| TERM 1 (Unit 1: Fundamentals of Protein Structure and X-ray Crystallography) | ||||
|---|---|---|---|---|
| Week | Date | Lecture | Topic | Lecturer(s) |
| 1 (2w) | 16-11 | Introduction & Web Authoring | Overview of Protein Crystallography & Bioinformatics (RasMol, Mime, HTML, Images, BioMOO) | HPCD, DSM |
| 2 | 30-11 | Protein Structure I | Primary Structure & Amino Acid and Peptide Bond Geometry | HPCD |
| 3 | 7-12 | Protein Structure II | Non-Covalent (Non-Bonded) Interactions | HPCD |
| 4 | 14-12 | X-Ray Diffraction I | Diffraction Theory (Scattering, Unit Cell, Braggs Law, Reciprocal Space, Indices, Structure Factor) | IJT |
| Break | ||||
| 5 | 5-1 | Protein Structure III | Secondary Structure & Super Secondary Structure | HPCD |
| 6 (2w) | 11-1 | X-Ray Diffraction II | Fourier Transforms (Synthesis, Analysis, Convolutions, Correlations) | IJT |
| 7 | 25-1 | Protein Structure IV | Tertiary Structure & Quaternary Structure (Point Groups) | HPCD |
| 8 | 1-2 | Symmetry I | Symmetry Operations (Rotational, Translational, Screw, Symbols, Unit Cell) | JKC, HPCD |
| 9 (2w) | 8-2 | Symmetry II | Point Groups (Enantiomorphic, Polar, Laue Classes) | JKC, HPCD |
| 10 | 22-2 | Protein Crystallography I | Protein Crystallisation | HPCD |
| 11 | 1-3 | Symmetry III | Space Groups (Enantiomorphic, Asymmetric Unit, P21, P212121) | JKC, HPCD |
| Break | ||||
| TERM 2 (Unit 2: Protein Crystallography) | ||||
| Week | Date | Lecture | Topic | Lecturer responsible |
| 1 | 15-3 | Protein Crystallography II | X-Rays, X-Ray Sources (Laboratory, Synchrotron) & X-Ray Detectors (Image Plate, CCD) | HPCD, JKC |
| 2 | 22-3 | Protein Crystallography III | Data Collection (Oscillation Method) & Cryocrystallography | HPCD |
| 3 | 29-3 | Symmetry IV & Protein Crystallography IV | Extinctions, Space Group Determination & Data Processing | HPCD, JKC |
| Break | ||||
| 4 | 12-4 | Protein Crystallography V & X-Ray Diffraction III | Molecular Replacement (Rotation Function, Translation Function), Patterson | HPCD |
| 5 | 19-4 | Project B | Project B Molecular Replacement | IJT, HPCD |
| Break | ||||
| 6 | 4-5 | Protein Crystallography VI & X-Ray Diffraction IV | Isomorphous Replacement, Patterson | HPCD |
| 7 (2w) | 10-5 | Protein Crystallography VII & X-Ray Diffraction V | MAD, Anomalous Diffraction | HPCD, IJT |
| 8 | 24-5 | Protein Crystallography VIII | Density Modification | HPCD |
| Break | ||||
| 9 | 7-6 | Protein Crystallography IX | Electron Density Map, Modelling & Refinement | HPCD |
| 10 | 14-6 | Protein Crystallography X | Validation & PDB | HPCD |
| 14-6 | Deadline for submission of Exam students to Registry | |||
| Break | ||||
| TERM 3 (Unit 3: Project) | ||||
| Week | Date | Lecture | Topic | Lecturer responsible |
| 1 | 21-6 | Protein Crystallography XI & Project A | Paper Contents (Understanding Crystallographic Results)
Project A Paper Abstract | HPCD |
| 1-10 | Months 6/7/8/9 | Project A | Project Work | IJT, HPCD |
| 1-10 | Months 4/5/6/7/8/9 | Project B | Project Work | IJT, HPCD |
| Break | ||||
| 13-9 | WRITTEN EXAMINATIONS | |||
| Break | ||||
| 20-10 | SUBMISSION OF PROJECT WORK | |||
| by Christmas | CERTIFICATES AWARDED | |||
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