School of Crystallography,
Birkbeck College,
University of London
Reload your browser every time you look at this page, especially if you are using the cache of your browser! There may be changes to the timetable which affect your time planning.
Normally lectures will be made available at the beginning of the week. Week numbers are sequential per term. Each TERM roughly coincides with a particular unit. There will be deviations for a few individual lectures, in order to pace delivery of more difficult subjects. Some "weeks" in Terms 1 and 2 have a release which is intended to be studied over a 2-week period. "Weeks" and "Lectures" in Term 3 are only nominal, as the projects are self-paced.
Official start date November 1st.
Please complete enrolment including payment by Wednesday December 1st.
Closure date for applications Wednesday December 1st.
TERM 1 (Unit 1: Fundamentals of Protein Structure and X-ray Crystallography) | ||||||||||||||||||||||||||||||||||||||
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Week | Date | Lecture | Topic | Lecturer responsible | ||||||||||||||||||||||||||||||||||
1-2 | 01-11 | Introduction & Web Authoring | Overview of Protein Crystallography & Bioinformatics (RasMol, Mime, HTML, Images, BioMOO) | TEB | ||||||||||||||||||||||||||||||||||
1-2 | 01-11 | Protein Structure I | Primary Structure & Amino Acid and Peptide Bond Geometry | TEB | ||||||||||||||||||||||||||||||||||
3 | 01-11 | Protein Structure II | Non-Covalent (Non-Bonded) Interactions | TEB | ||||||||||||||||||||||||||||||||||
4 | 22-11 | Protein Structure III | Secondary Structure, Super Secondary Structure and Tertiary Structure | TEB | ||||||||||||||||||||||||||||||||||
5 | 29-11 | Protein Structure IV | Quaternary Structure (Point Groups) | TEB, JKC | ||||||||||||||||||||||||||||||||||
6 | 6-12 | X-Ray Diffraction I and the CCP4 Gui | Diffraction Theory (Scattering, Unit Cell, Braggs Law, Reciprocal Space, Indices, Structure Factor) and using the CCP4 Gui | TEB | ||||||||||||||||||||||||||||||||||
Christmas Break | ||||||||||||||||||||||||||||||||||||||
7 | 10-1 | Symmetry I | Symmetry Operations (Rotational, Translational, Screw, Symbols, Unit Cell) | JKC, TEB | ||||||||||||||||||||||||||||||||||
8-9 | 17-1 | Symmetry II | Point Groups (Enantiomorphic, Polar, Laue Classes) | JKC, TEB | ||||||||||||||||||||||||||||||||||
10 | 31-1 | Protein Crystallography I | Protein Crystallisation | TEB | ||||||||||||||||||||||||||||||||||
11-12 | 7-2 | Symmetry III | Space Groups (Enantiomorphic, Asymmetric Unit, P21, P212121) | JKC, TEB | ||||||||||||||||||||||||||||||||||
13 | 21-2 | Protein Crystallography II | X-Rays, X-Ray Sources (Laboratory, Synchrotron) & X-Ray Detectors (Image Plate, CCD). | TEB, JKC | ||||||||||||||||||||||||||||||||||
Break | ||||||||||||||||||||||||||||||||||||||
TERM 2 (Unit 2: Protein Crystallography) | ||||||||||||||||||||||||||||||||||||||
Week | Date | Lecture | Topic | Lecturer responsible | ||||||||||||||||||||||||||||||||||
1 | 7-3 | Protein Crystallography III | Data Collection (Oscillation Method) & Cryocrystallography | NQM | ||||||||||||||||||||||||||||||||||
2-3 | 14-3 | Symmetry IV & Protein Crystallography IV | Extinctions, Space Group Determination & Data Processing | TEB, JKC | ||||||||||||||||||||||||||||||||||
Easter Break | ||||||||||||||||||||||||||||||||||||||
4-5 | 18-4 | X-Ray Diffraction II | Fourier Transforms (Synthesis, Analysis, Convolutions, Correlations) | TEB | ||||||||||||||||||||||||||||||||||
6 | 3-5 | Protein Crystallography V & X-Ray Diffraction III | Molecular Replacement (Rotation Function, Translation Function), Patterson | NQM | ||||||||||||||||||||||||||||||||||
7 | 9-5 | Protein Crystallography VI | Isomorphous Replacement, Patterson | NQM | ||||||||||||||||||||||||||||||||||
8-9 | 16-5 | Protein Crystallography VII & X-Ray Diffraction V | MAD, Anomalous Diffraction | NQM, | ||||||||||||||||||||||||||||||||||
10 | 1-6 | Protein Crystallography VIII | Density Modification | NQM | ||||||||||||||||||||||||||||||||||
11 | 6-5 | Protein Crystallography IX | Electron Density Map, Modelling & Refinement | NQM | ||||||||||||||||||||||||||||||||||
12 | 13-6 | Protein Crystallography X | Validation & PDB | NQM | ||||||||||||||||||||||||||||||||||
TERM 3 (Unit 3: Project) | ||||||||||||||||||||||||||||||||||||||
Week | Date | Lecture | Topic | Lecturer responsible | ||||||||||||||||||||||||||||||||||
1 | 20-6 | Protein Crystallography XI & Project A | Papers & Understanding Crystallographic Results
Project A Paper Abstract | 1 | 27-6
| Project B
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Project B Molecular Replacement
| 1-10 | Months 6/7/8/9/10
| Project A & B | Project Work
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| Break
| September 22nd | WRITTEN EXAMINATIONS
| Break
| October | SUBMISSION OF PROJECT WORK
| by Christmas | CERTIFICATES AWARDED
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