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Postgraduate  Certificate  in  Protein  Crystallography  on  the  Web 
Timetable  Lectures  01/02 

School of CrystallographyBirkbeck College
University of London



Normally lectures will be made available at the beginning of the week. Week numbers are sequential per term. Each TERM roughly coincides with a particular unit. There will be deviations for a few individual lectures, in order to pace delivery of more difficult subjects. Some "weeks" in Terms 1 and 2 have a release which is intended to be studied over a 2-week period. "Weeks" and "Lectures" in Term 3 are only nominal, as the projects are self-paced.

Official start date Monday November 12th.
Enrolment including payment must be completed by Thursday November 29th.

TERM 1 (Unit 1: Fundamentals of Protein Structure and X-ray Crystallography)
WeekDateLecture TopicLecturer responsible
1-2 12-11 Introduction & Web Authoring Overview of Protein Crystallography & Bioinformatics (JMol, HTML, Images, IMS) HPCD
1-2 12-11 Protein Structure I Primary Structure & Amino Acid and Peptide Bond Geometry HPCD
3 26-11 Protein Structure II Non-Covalent (Non-Bonded) Interactions HPCD
4 3-12 X-Ray Diffraction I Diffraction Theory (Scattering, Unit Cell, Braggs Law, Reciprocal Space, Indices, Structure Factor) HPCD
5 10-12 Protein Structure III Secondary Structure & Super Secondary Structure HPCD
Christmas Break
6-7 7-1 X-Ray Diffraction II Fourier Transforms (Synthesis, Analysis, Convolutions, Correlations) HPCD
8 21-1 Protein Structure IV Tertiary Structure & Quaternary Structure (Point Groups) HPCD
9 29-10 Symmetry I Symmetry Operations (Rotational, Translational, Screw, Symbols, Unit Cell) JKC, HPCD
10-11 4-2 Symmetry II Point Groups (Enantiomorphic, Polar, Laue Classes) JKC, HPCD
12 18-2 Protein Crystallography I Protein Crystallisation HPCD
Break
TERM 2 (Unit 2: Protein Crystallography)
WeekDateLecture TopicLecturer responsible
1-2 11-3 Symmetry III Space Groups (Enantiomorphic, Asymmetric Unit, P21, P212121) JKC, HPCD
3 25-3 Protein Crystallography II X-Rays, X-Ray Sources (Laboratory, Synchrotron) & X-Ray Detectors (Image Plate, CCD) HPCD, JKC
Easter Break
4 15-4 Protein Crystallography III Data Collection (Oscillation Method) & Cryocrystallography HPCD
5-6 22-4 Symmetry IV & Protein Crystallography IV Extinctions, Space Group Determination & Data Processing HPCD, JKC
7 6-5 Protein Crystallography V & X-Ray Diffraction III Molecular Replacement (Rotation Function, Translation Function), Patterson HPCD
8 13-5 Protein Crystallography VI Isomorphous Replacement, Patterson HPCD
9-10 20-5 Protein Crystallography VII & X-Ray Diffraction IV MAD, Anomalous Diffraction HPCD, NQM
11 3-6 Protein Crystallography VIII Density Modification HPCD
12 10-6 Protein Crystallography IX Electron Density Map, Modelling & Refinement HPCD
12 17-6 Protein Crystallography X Validation & PDB HPCD
TERM 3 (Unit 3: Project)
WeekDate Lecture TopicLecturer responsible
1 24-6 Protein Crystallography XI & Project A Papers & Understanding Crystallographic Results
Project A Paper Abstract
HPCD
1 24-6 Project B Project B Molecular Replacement HPCD
1-10 Months 6/7/8/9/10 Project A & B Project Work HPCD
1 24-6 Protein Crystallography XI & Project A Papers & Understanding Crystallographic Results
Project A Paper Abstract
HPCD
1 24-6 Project B Project B Molecular Replacement HPCD
1-10 Months 6/7/8/9/10 Project A & B Project Work HPCD
Break
[25] September WRITTEN EXAMINATIONS
Break
[31] October SUBMISSION OF PROJECT WORK
by ChristmasCERTIFICATES AWARDED



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